For healthcare professionals

Scarless Silicone Gel — clinical resource

A reference page for surgeons, dermatologists, and other clinicians evaluating Scarless as a topical silicone gel for scar management. Sections below cover mechanism, evidence, how to use, safety profile, and counseling points. Composition percentages remain on the technical file (available on request).

At a glance

Clinical summary

Product class
Topical silicone scar gel — self-drying.
Indications
Appearance and management of new and established scars: surgical, C-section, burn, hypertrophic, and keloid-type scars. For acne scarring, raised acne scars only, as for any raised scar — not atrophic (pitted) marks. Growing or recurrent keloids, and scars that are painful or restrict movement, need medical evaluation and may require other treatments.
Key ingredients
A multi-silicone occlusive system, squalane (olive-derived emollient), and a stable vitamin C derivative.
Mechanism summary
An occlusive silicone film reduces transepidermal water loss and maintains stratum-corneum hydration. Published research on silicone gel associates these conditions with a softer, flatter, less-red scar. Squalane and vitamin C play supporting roles.
Drug status
Non-medicated topical. Works physically by occlusion; no pharmacologically active drug and no systemic absorption.
Positioning
A first-line topical option once a wound has closed — for patients seeking to improve the appearance of a new or established scar, including children and those with sensitive skin.
Standard application
Thin layer 2–3× daily after wound closure, for 2–3 months; established scars longer. See the Use section.
Marketed by
Goodness Care, Amman, Jordan.

Mechanisms of action

How the key ingredients work

Scarless combines a multi-silicone occlusive system with squalane and a stable vitamin C derivative. The silicone barrier is the primary mechanism; squalane and vitamin C play supporting roles described individually in the research.

Multi-silicone occlusive system

Topical silicone barrier

Several silicones act together: a fast-spreading silicone delivers a thin, even layer that then lifts away; a film-forming silicone sets into a flexible, breathable, water-resistant occlusive sheet; and a conditioning silicone keeps the film comfortable. The occlusive film reduces transepidermal water loss and maintains stratum-corneum hydration — the mechanism the published silicone research associates with softer, flatter, and less-red scars.

Clinical relevance

Primary mechanism for scar management. Supported by published research on topical silicone for post-operative, hypertrophic, and keloid scars, summarized on the Published Research page.

Stable vitamin C derivative

Oil-stable vitamin C derivative

A stable, oil-compatible vitamin C derivative. Published research on this ingredient describes antioxidant activity and a role in collagen formation and skin-tone appearance.

Clinical relevance

Supporting role within the formulation; its antioxidant activity and role in collagen formation and skin tone are documented in published research on this ingredient. See the silicone-and-vitamin-C formulation study and the ascorbic-acid wound-healing research on the Published Research page.

Vitamin C findings derive from research on the ingredient and on a related silicone-and-vitamin-C formulation, not from a trial of Scarless itself.

Squalane

Olive-derived emollient

Squalane is a lightweight, skin-identical emollient that restores moisture and offsets the dryness long-term silicone-only use can cause, keeping the barrier comfortable for daily wear.

Clinical relevance

Supporting role for comfort and barrier tolerability over a full course. Squalane's emollient and antioxidant activity is documented in published dermatology research.

Published research summary

Published research across the key ingredients and related formulations

Mechanism and outcome data on Scarless's key ingredients come from peer-reviewed published research, summarized with citations and PubMed identifiers on the Published Research page. The published research describes the individual key ingredients and related silicone-and-vitamin-C formulations.

  • Advanced-formula silicone gel for post-operative scar prevention
  • Silicone gel for early scar intervention
  • Silicone gel with vitamin C for scar appearance
  • Topical silicone gel vs. silicone gel sheet
  • Ascorbic acid, collagen synthesis, and wound healing
  • Squalane: antioxidant and emollient activity

Use & application

How to use by scar age

Scarless is applied as a thin layer to clean, dry skin. Start on intact skin once the wound has fully closed and sutures are removed — typically at least two weeks after surgery, and as judged by the surgeon. The application is constant; what varies is how long the course runs with the age and type of scar. Allow each layer to dry before covering with clothing or makeup.

New scars

Amount
Thin layer
Frequency
2–3× daily
Course length
2–3 months

Best for

New scars, once the wound has fully closed and sutures are removed, with healing status, not day count, governing when to start.

Clean and fully dry the area, apply a thin layer, and allow it to dry (a few minutes) before dressing. Scarless may be worn under clothing and makeup once dry.

Begin only after wound closure. Improvement in scar appearance is gradual; reassess at 6–8 weeks.

Established & older scars

Amount
Thin layer
Frequency
2–3× daily
Course length
3 months or longer

Best for

Older, established, hypertrophic, or keloid-type scars. Growing or recurrent keloids, and scars that are painful or restrict movement, need medical evaluation and may require other treatments.

Same thin-layer application as for new scars. Older scars typically need a longer, consistent course.

Set expectations for a multi-week course. If a scar is enlarging, painful, or spreading beyond the original wound, assess before continuing.

Children & sensitive skin

Amount
Thin layer
Frequency
2–3× daily
Course length
Per scar age

Best for

Children and patients with sensitive skin, on new or established scars.

The silicone barrier can be used in children and those with sensitive skin once the wound has fully healed; consider a patch test first. No minimum age is established in the approved product documentation.

Apply to intact skin only and discontinue if irritation develops.

Safety profile

Topical — favorable safety in routine use

Scarless's safety profile follows from its topical nature, which limits the contexts in which contraindications or interactions apply. The blocks below cover what clinicians need in routine practice.

Contraindications & cautions

Do not apply to open wounds, unhealed incisions, or before sutures are removed — wait until the wound has fully closed and sutures are removed, with healing status, not day count, governing when to start. Avoid broken or infected skin and active dermatitis at the site. Avoid contact with the eyes and mucous membranes. Discontinue if irritation or hypersensitivity to silicone occurs (rare). For external topical use only.

Interactions

None expected. As a non-medicated topical, Scarless has no documented systemic drug interactions. Where other topical products are used on the same area, follow each product's instructions and assess whether using them together is appropriate.

Adverse effects

Any reaction to topical silicone is typically limited to mild local irritation. No published surveillance data specific to Scarless exists; report any unusual reaction. Discontinue if irritation persists or worsens.

Patient counseling

Eight points for discussing Scarless with patients

Practical guidance for the conversations clinicians have with patients about Scarless. These eight points cover when to start, expectation-setting, technique, and follow-up — drawn from common clinical conversations and the editorial conventions of this resource. Each can be cited by number in clinical notes or shared with practice staff.

  1. Start only after the wound has fully closed and any sutures are removed. Scarless is for intact skin, not open or healing wounds.

  2. Set realistic expectations for both timing and outcome. Improvement in a scar's appearance is gradual, over weeks to months. The recommended course is 2–3 months of consistent use; older, established scars often need longer. Scarless helps soften, flatten, and fade the appearance of a scar; it is not a guarantee of complete removal. Frame it as improvement, not erasure.

  3. Confirm technique: clean and fully dry the area, apply a thin layer, and let it dry before covering. A thin film is enough — more product does not speed results.

  4. Reinforce frequency and adherence: a thin layer 2–3 times a day. Consistency across the full course matters more than any single application. Encourage the patient to tie applications to a settled daily routine.

  5. Reassure on suitability. The silicone barrier can be used in children and sensitive skin once the wound has fully healed; suggest a patch test where sensitivity is a concern.

  6. Lead with the physical mechanism for cautious patients. The silicone film works physically by occlusion and contains no medication, which often settles concerns about layering on a healing area.

  7. Mention practicality. Once dry, Scarless can be worn under clothing and makeup, which makes a 2–3-times-a-day routine realistic to sustain.

  8. Set a follow-up point — around 6–8 weeks — to review progress and tolerability. Advise patients to return sooner if a scar enlarges, becomes painful, or shows signs of infection.

Patient-facing pages you can share: