For healthcare professionals

Scarless Silicone Gel — clinical resource

A reference page for surgeons, dermatologists, pharmacists, and other clinicians evaluating Scarless as a topical silicone gel for scar management. Sections below cover mechanism, evidence, dosing, safety profile, and counseling points. Composition percentages remain on the technical file (available on request).

At a glance

Clinical summary

Product class: Topical silicone scar gel — drug-free, self-drying.
Indications: Appearance and management of new and established scars: surgical, C-section, burn, hypertrophic and keloid-type, and acne scars.
Key components: A multi-silicone occlusive system, squalane (olive-derived emollient), and a stable vitamin C derivative.
Mechanism summary: An occlusive silicone film reduces transepidermal water loss and maintains stratum-corneum hydration — the conditions the published research associates with normalized collagen synthesis and a softer, flatter, less-red scar. Squalane and vitamin C play supporting roles.
Drug status: Non-medicated topical. Works physically by occlusion; no pharmacologically active drug and no systemic absorption.
Positioning: A first-line topical option once a wound has closed — for patients seeking to improve the appearance of a new or established scar, including children and those with sensitive skin.
Standard dosing: Thin layer 2–3× daily after wound closure, for 2–3 months; established scars longer. See the Dosing section.
Marketed by: Goodness Care, Amman, Jordan. Made in Jordan in GMP-certified facilities.

Mechanisms of action

How the actives work

Scarless combines a multi-silicone occlusive system with squalane and a stable vitamin C derivative. The silicone barrier is the primary mechanism; squalane and vitamin C play supporting roles described individually in the research.

Multi-silicone occlusive system

Topical silicone barrier

Several silicones act together: a fast-spreading silicone delivers a thin, even layer that then lifts away; a film-forming silicone sets into a flexible, breathable, water-resistant occlusive sheet; and a conditioning silicone keeps the film comfortable. The occlusive film reduces transepidermal water loss and maintains stratum-corneum hydration — the mechanism the published silicone research associates with softer, flatter, and less-red scars.

Clinical relevance

Primary mechanism for scar management. Supported by published research on topical silicone for post-operative, hypertrophic, and keloid scars, summarized on the Clinical Evidence page.

Stable vitamin C derivative

Oil-stable vitamin C derivative

A stable, oil-compatible vitamin C derivative provides antioxidant support and is associated, in the research on the active, with collagen organization and more even skin tone.

Clinical relevance

Supporting role for scar tone and collagen organization. See the silicone-and-vitamin-C formulation study and the ascorbic-acid wound-healing research on the Clinical Evidence page.

Vitamin C findings derive from research on the active and on a related silicone-and-vitamin-C formulation, not from a trial of Scarless itself.

Squalane

Olive-derived emollient

Squalane is a lightweight, skin-identical emollient that restores moisture and offsets the dryness long-term silicone-only use can cause, keeping the barrier comfortable for daily wear.

Clinical relevance

Supporting role for comfort and barrier tolerability over a full course. Squalane's emollient and antioxidant activity is documented in published dermatology research.

Clinical evidence summary

Published research across the actives and related formulations

Mechanism and outcome data on Scarless's actives come from peer-reviewed published research, summarized with citations and PubMed identifiers on the Clinical Evidence page. The published research describes the individual actives and related silicone-and-vitamin-C formulations; Scarless itself has not been evaluated in a randomized controlled trial.

Advanced-formula silicone gel for post-operative scar prevention
Silicone gel for early scar intervention
Silicone gel with vitamin C for scar appearance
Topical silicone gel vs. silicone gel sheet
Ascorbic acid, collagen synthesis, and wound healing
Squalane: antioxidant and emollient activity

See full clinical evidence

Dosing & administration

How to dose by scar age

Scarless is applied as a thin layer to clean, dry, intact skin once the wound has fully closed and any sutures are removed (~2 weeks post-op). The application is constant; what varies is how long the course runs with the age and type of scar. Allow each layer to dry before covering with clothing or makeup.

New scars

Amount: Thin layer
Frequency: 2–3× daily
Course length: 2–3 months

Best for

New scars, once the wound has fully closed and sutures are removed (~2 weeks post-op).

Clean and fully dry the area, apply a thin layer, and allow it to dry (a few minutes) before dressing. Scarless may be worn under clothing and makeup once dry.

Begin only after wound closure. Improvement in scar appearance is gradual; reassess at 6–8 weeks.

Established & older scars

Amount: Thin layer
Frequency: 2–3× daily
Course length: 3 months or longer

Best for

Older, established, hypertrophic, or keloid-type scars.

Same thin-layer application as for new scars. Older scars typically need a longer, consistent course.

Set expectations for a multi-week course. If a scar is enlarging, painful, or spreading beyond the original wound, assess before continuing.

Children & sensitive skin

Amount: Thin layer
Frequency: 2–3× daily
Course length: Per scar age

Best for

Children and patients with sensitive skin, on new or established scars.

The drug-free silicone barrier is suitable for children and sensitive skin. A patch test is reasonable where sensitivity is a concern.

Apply to intact skin only and discontinue if irritation develops.

Safety profile

Topical, drug-free — favorable safety in routine use

Scarless's safety profile follows from its topical, drug-free nature. Topical silicone is not systemically absorbed, which limits the contexts in which contraindications or interactions apply. The blocks below cover what clinicians need in routine practice.

Contraindications & cautions

Do not apply to open wounds, unhealed incisions, or before sutures are removed — wait until the wound has fully closed (~2 weeks post-op). Avoid broken or infected skin and active dermatitis at the site. Avoid contact with the eyes and mucous membranes. Discontinue if irritation or hypersensitivity to silicone occurs (rare). For external topical use only.

Interactions

None expected. As a non-medicated topical that is not systemically absorbed, Scarless has no documented systemic drug interactions. It may be used alongside other topical scar measures; allow each product to dry before layering.

Pregnancy & breastfeeding

Topical silicone is not systemically absorbed, so Scarless is suitable as a topical during pregnancy and breastfeeding, subject to the usual advice to discuss any product with the treating clinician. Apply only to intact skin and avoid the immediate nipple–areola area while breastfeeding.

Adverse effects

Adverse effects are uncommon and typically mild — usually transient local irritation or itching at the application site, and rarely contact sensitivity to silicone. Serious adverse events have not been reported with routine topical use. Discontinue if irritation persists or worsens.

Special populations

Children & sensitive skin: suitable; a drug-free silicone barrier with a patch test where sensitivity is a concern. Elderly patients: appropriate at standard use. Renal or hepatic impairment: no adjustment — topical application carries no systemic load. Apply to intact skin only.

Patient counseling

Ten points for discussing Scarless with patients

Practical guidance for the conversations clinicians have with patients about Scarless. These ten points cover when to start, expectation-setting, technique, and follow-up — drawn from common clinical conversations and the editorial conventions of this resource. Each can be cited by number in clinical notes or shared with practice staff.

Start only after the wound has fully closed and any sutures are removed — usually about two weeks post-op. Scarless is for intact skin, not open or healing wounds.
Set realistic timing. Improvement in a scar's appearance is gradual, over weeks to months. The recommended course is 2–3 months of consistent use; older, established scars often need longer.
Be clear about outcomes. Scarless helps soften, flatten, and fade the appearance of a scar; it is not a guarantee of complete removal. Frame it as improvement, not erasure.
Confirm technique: clean and fully dry the area, apply a thin layer, and let it dry before covering. A thin film is enough — more product does not speed results.
Reinforce frequency: a thin layer 2–3 times a day. Consistency across the full course matters more than any single application.
Adherence is the main driver. Encourage tying application to daily routines (morning and evening) so the course is completed; missed days, not dose size, are the usual reason for disappointing results.
Reassure on suitability. The drug-free silicone barrier is gentle enough for children and sensitive skin; suggest a patch test where sensitivity is a concern.
Lead with the drug-free mechanism for cautious patients. The silicone film works physically by occlusion — no medication and no systemic exposure — which often settles concerns about layering on a healing area.
Mention practicality. Once dry, Scarless can be worn under clothing and makeup, which makes a two- or three-times-daily routine realistic to sustain.
Set a follow-up point — around 6–8 weeks — to review progress and tolerability. Advise patients to return sooner if a scar enlarges, becomes painful, or shows signs of infection.

Patient-facing pages you can share:

One more thing

Have a clinical question?

Our medical affairs team is available for any question about Scarless — mechanism, dosing, safety in specific populations, study collaboration, adverse event reporting, or topics this resource didn't address.

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