For healthcare professionals

Scarless Silicone Gel — clinical resource

A reference page for surgeons, dermatologists, and other clinicians evaluating Scarless as a topical silicone gel for scar management. Sections below cover mechanism, evidence, how to use, safety profile, and counseling points. Composition percentages remain on the technical file (available on request).

At a glance

Clinical summary

Product class: Topical silicone scar gel — self-drying.
Indications: Appearance and management of new and established scars: surgical, C-section, burn, hypertrophic, and keloid-type scars. For acne scarring, raised acne scars only, as for any raised scar — not atrophic (pitted) marks. Growing or recurrent keloids, and scars that are painful or restrict movement, need medical evaluation and may require other treatments.
Key ingredients: A multi-silicone occlusive system, squalane (olive-derived emollient), and a stable vitamin C derivative.
Mechanism summary: An occlusive silicone film reduces transepidermal water loss and maintains stratum-corneum hydration. Published research on silicone gel associates these conditions with a softer, flatter, less-red scar. Squalane and vitamin C play supporting roles.
Drug status: Non-medicated topical. Works physically by occlusion; no pharmacologically active drug and no systemic absorption.
Positioning: A first-line topical option once a wound has closed — for patients seeking to improve the appearance of a new or established scar, including children and those with sensitive skin.
Standard application: Thin layer twice daily, morning and evening, after wound closure, for 2–3 months; established scars longer. See the Use section.
Marketed by: Goodness Care, Amman, Jordan.

Mechanisms of action

How the key ingredients work

Scarless combines a multi-silicone occlusive system with squalane and a stable vitamin C derivative. The silicone barrier is the primary mechanism; squalane and vitamin C play supporting roles described individually in the research.

Multi-silicone occlusive system

Topical silicone barrier

Several silicones act together: a fast-spreading silicone delivers a thin, even layer that then lifts away; a film-forming silicone sets into a flexible, breathable, water-resistant occlusive sheet; and a conditioning silicone keeps the film comfortable. The occlusive film reduces transepidermal water loss and maintains stratum-corneum hydration — the mechanism the published silicone research associates with softer, flatter, and less-red scars.

Clinical relevance

Primary mechanism for scar management. Supported by published research on topical silicone for post-operative, hypertrophic, and keloid scars, summarized on the Published Research page.

Stable vitamin C derivative

Oil-stable vitamin C derivative

A stable, oil-compatible vitamin C derivative. Published research on vitamin C (ascorbic acid, in an animal wound model) and on a different silicone-plus-vitamin-C gel describes antioxidant activity and roles in collagen formation and skin tone. These findings have not been shown for this derivative or for Scarless.

Clinical relevance

Supporting role within the formulation; its contribution to scar outcomes has not been established in a trial of Scarless. See the ascorbic-acid study and the related-formulation study on the Published Research page for what was actually studied.

Vitamin C findings derive from research on the ingredient and on a related silicone-and-vitamin-C formulation, not from a trial of Scarless itself.

Squalane

Olive-derived emollient

Squalane is a lightweight emollient included for skin comfort, keeping the film comfortable for daily wear over a full course.

Clinical relevance

Supporting role for comfort and tolerability. A narrative review describes squalane's emollient properties; it has not been tested for scar outcomes.

Published research summary

Published research across the key ingredients and related formulations

Mechanism and outcome data on Scarless's key ingredients come from peer-reviewed published research, summarized with citations and PubMed identifiers on the Published Research page. The published research describes the individual key ingredients and related silicone-and-vitamin-C formulations.

Advanced-formula silicone gel for post-operative scar prevention
Silicone gel for early scar intervention
Silicone gel with vitamin C for scar appearance
Topical silicone gel vs. silicone gel sheet
Ascorbic acid, collagen synthesis, and wound healing
Squalane: antioxidant and emollient activity

See full published research

Use & application

How to use by scar age

Scarless is applied as a thin layer to clean, dry skin. Start on intact skin once the wound has fully closed, is dry and sutures or staples are out — often about two weeks after surgery, but the surgeon's assessment comes first; never on an open or unhealed wound. The application is constant; what varies is how long the course runs with the age and type of scar. Allow each layer to dry before covering with clothing or makeup.

New scars

Amount: Thin layer
Frequency: Twice daily, morning and evening
Course length: 2–3 months

Best for

New scars, once the wound has fully closed, is dry and sutures or staples are out — often about two weeks after surgery, but the surgeon's assessment comes first.

Clean and fully dry the area, apply a thin layer, and allow it to dry (a few minutes) before dressing. Scarless may be worn under clothing and makeup once dry.

Begin only after wound closure. Improvement in scar appearance is gradual. Practical guidance: review progress at around 6–8 weeks.

Established & older scars

Amount: Thin layer
Frequency: Twice daily, morning and evening
Course length: 3 months or longer

Best for

Older, established, hypertrophic, or keloid-type scars. Growing or recurrent keloids, and scars that are painful or restrict movement, need medical evaluation and may require other treatments.

Same thin-layer application as for new scars. Older scars typically need a longer, consistent course.

Set expectations for a multi-week course. If a scar is enlarging, painful, or spreading beyond the original wound, assess before continuing.

Children & sensitive skin

Amount: Thin layer
Frequency: Twice daily, morning and evening
Course length: Per scar age

Best for

Children and patients with sensitive skin, on new or established scars.

The silicone barrier can be used in children and those with sensitive skin once the wound has fully healed; consider a patch test first. No minimum age is established in the approved product documentation.

Apply to intact skin only and discontinue if irritation develops.

Safety profile

Topical — local skin reactions are rare

Scarless's safety profile follows from its topical nature, which limits the contexts in which contraindications or interactions apply. The blocks below cover what clinicians need in routine practice.

Contraindications & cautions

Do not apply to open wounds, unhealed incisions, or before sutures are removed — start once the wound has fully closed, is dry and sutures or staples are out, often about two weeks after surgery, but the surgeon's assessment comes first. Contraindicated in known hypersensitivity to silicone-based products. Avoid broken or infected skin and active dermatitis at the site. Avoid contact with the eyes and mucous membranes. Discontinue if irritation or hypersensitivity to silicone occurs (rare). For external topical use only.

Interactions

None expected. As a non-medicated topical, Scarless has no documented systemic drug interactions. Where other topical products are used on the same area, follow each product's instructions and assess whether using them together is appropriate.

Adverse effects

The product information lists undesirable effects as rare: local redness, itching or irritation at the application site. No published surveillance data specific to Scarless exists; report any unusual reaction. Advise patients to stop use if these effects occur and to seek advice if they persist.

Patient counseling

Eight points for discussing Scarless with patients

Practical guidance for the conversations clinicians have with patients about Scarless. These eight points cover when to start, expectation-setting, technique, and follow-up — drawn from common clinical conversations and the editorial conventions of this resource. Each can be cited by number in clinical notes or shared with practice staff.

Start only after the wound has fully closed and any sutures are removed. Scarless is for intact skin, not open or healing wounds.
Set realistic expectations for both timing and outcome. Improvement in a scar's appearance is gradual, over weeks to months. The recommended course is 2–3 months of consistent use; older, established scars often need longer. Scarless helps prevent, reduce and flatten scars; it is not a guarantee of complete removal. Frame it as improvement, not erasure.
Confirm technique: clean and fully dry the area, apply a thin layer, and let it dry before covering. A thin film is enough — more product does not speed results.
Reinforce frequency and adherence: a thin layer twice a day, morning and evening. Consistency across the full course matters more than any single application. Encourage the patient to tie applications to a settled daily routine.
Reassure on suitability. The silicone barrier can be used in children and sensitive skin once the wound has fully healed; suggest a patch test where sensitivity is a concern.
Lead with the physical mechanism for cautious patients. The silicone film works physically by occlusion and contains no medication, which often settles concerns about layering on a healing area.
Mention practicality. Once dry, Scarless can be worn under clothing and makeup, which makes a twice-daily routine realistic to sustain.
Set a follow-up point — around 6–8 weeks — to review progress and tolerability. Advise patients to return sooner if a scar enlarges, becomes painful, or shows signs of infection.

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